SAINT® Depression Therapy is a non-drug, noninvasive treatment delivering rapid remission from major depressive disorder in just five days—even for people who haven’t responded to conventional treatments.

  HOW IT WORKS

SAINT Depression Therapy

When depression doesn’t respond to medication or conventional therapy, SAINT offers hope: an FDA-cleared treatment that uses gentle magnetic pulses to target the brain region involved in depression.
Find a provider
  WHY SAINT

Helping people get better, faster.

8 in 10

people experienced remission from their depression in a randomized clinical trial. 

2.6 days

to remission on average. 

6

medications failed on average among trial participants.

FDA-cleared

Unlike traditional treatments that can take weeks or months to start working, SAINT can bring meaningful relief from depression in days.

Depression isn’t just a chemical imbalance — it’s a problem within the brain’s communication network.
In people with major depressive disorder, the connections between key areas that control mood and emotion stop working properly, creating patterns of overactivity or disconnection that keep the brain “stuck” in a depressed state.

Understanding depression at the brain level

Medications change brain chemistry broadly, which can take weeks or months and may not work after multiple trials.
Ketamine or esketamine act quickly but temporarily, often requiring ongoing dosing and carrying dissociative side effects.
Standard TMS is more precise than medication but usually takes 6–9 weeks of daily sessions and doesn’t individualize the target area.
Traditional treatments work more slowly or less precisely

A better path to lasting depression relief

What people are saying about SAINT

Living with depression can feel isolating and exhausting — especially when other treatments haven’t worked. SAINT is giving people their lives back, offering a fast, noninvasive path to remission that helps patients feel like themselves again within days. 

  TESTIMONIALS

"A few days after I started the treatment. I didn’t feel the urge to go back to my hotel room and get in bed, or turn on the tv. I went out walking and shopping. Music sounded a little sweeter when I was shopping. I got hungry, which for me is a good sign because my body had a hard time eating when I feel depressed or anxious. You feel changes the week you do the treatment. I wish I had done it 20 years ago instead of putting myself through cycles of pills."

Caroline N.

Verified SAINT Patient

  LEARN MORE

Ready to find a SAINT provider near you?

Copyright © 2025
Find a provider
CONSULTATION
01
Meet with a trained SAINT® provider to review your history and determine if this therapy is right for you.
02
PERSONAL BRAIN MAPPING
A functional MRI (fMRI) scan identifies the exact area of your brain involved in depression.
03
PRECISION TARGETING
Magnus Medical’s software uses your brain map to guide stimulation precisely to that spot — unique to you.
04
ACCELERATED 5-DAY TREATMENT
Receive short, noninvasive sessions over five consecutive days — no anesthesia, no downtime.
05
RAPID, LASTING RESULTS
Most patients experience meaningful relief within days, with results that can last long after treatment ends.
combines the speed of ketamine with the precision of imaging-guided neuromodulation — and delivers lasting remission without drugs or anesthesia.

SAINT®

Find a provider

AJ Manett, MD

“Having another option for someone who’s really desperate and feeling like they’re at the end of their rope, it’s a really good feeling to have as a provider who can tell somebody, ‘I have a lot of confidence that we can help.’”
Assistant Professor Psychiatry
Medical University of South Carolina

Mohammad Ahmed, MD

Founder &. CEO | Kaizen Brain Center
“The typical patients who come for SAINT are people who struggle with really severe depression… tried multiple medications, tried TMS before. We’ve also had patients who’ve actually failed ECT, which was the gold standard treatment. And we’ve seen better outcomes with SAINT.”

Rebecca Allen, MD MTH

Director of Neuropsychiatry & Research
Seattle NTC
“...We know that SAINT has a better response and remission rate than the standard daily protocol of TMS for depression.”

Ian Cook, MD DLFAPA

Founder & Director
Los Angeles TMS Institute
“One of our SAINT patients was a psychologist who had struggled with depression all of her adult life. And after decades of struggle… she did SAINT and after a couple weeks had this lightbulb moment of ‘the symptoms are gone. This is the best I’ve felt my entire life.”

A breakthrough clinicians believe in

  HOW IT WORKS

SAINT Depression Therapy

When depression doesn’t respond to medication or conventional therapy, SAINT offers hope: an FDA-cleared treatment that uses gentle magnetic pulses to target the brain region involved in depression. 


It takes 4 steps to start feeling like yourself again.
Find a provider
Find a provider
STEP 1: Consultation 
STEP 2: Functional MRI brain scan 
STEP 3: Individualized targeting
STEP 4: 5-day stimulation series

A better path to lasting depression relief.

SAINT® Depression Therapy is a non-drug, noninvasive treatment delivering rapid remission from major depressive disorder in just five days—even for people who haven’t responded to conventional treatments.

  HOW IT WORKS

SAINT Depression Therapy

When depression doesn’t respond to medication or conventional therapy, SAINT offers hope: an FDA-cleared treatment that uses gentle magnetic pulses to target the brain region involved in depression. 
It takes 4 steps to start feeling like yourself again.
STEP 1: Consultation 
STEP 2: Functional MRI brain scan 
STEP 3: Individualized targeting
STEP 4: 5-day stimulation series
  WHY SAINT

Helping people get better, faster.

8 in 10

people experienced remission from their depression in a randomized clinical trial.

2.6 days

to remission on average. 

FDA-cleared

Unlike traditional treatments that can take weeks or months to start working, SAINT can bring meaningful relief from depression symptoms in days.

What people are saying about SAINT

Living with depression can feel isolating and exhausting — especially when other treatments haven’t worked. SAINT is giving people their lives back, offering a fast, noninvasive path to remission that helps patients feel like themselves again within days.

  TESTIMONIALS

"A few days after I started the treatment. I didn’t feel the urge to go back to my hotel room and get in bed, or turn on the tv. I went out walking and shopping. Music sounded a little sweeter when I was shopping. I got hungry, which for me is a good sign because my body had a hard time eating when I feel depressed or anxious. You feel changes the week you do the treatment. I wish I had done it 20 years ago instead of putting myself through cycles of pills."

Caroline N.

Verified SAINT Patient

AJ Manett, MD

Assistant Professor Psychiatry
Medical University of South Carolina

Mohammad Ahmed, MD

Founder &. CEO | Kaizen Brain Center

Rebecca Allen, MD MTH

Director of Neuropsychiatry & Research | Seattle NTC

Ian Cook, MD DLFAPA

Founder & Director
Los Angeles TMS Institute

A breakthrough clinicians believe in

6

medications failed on average among trial participants.

  LEARN MORE

Ready to find a SAINT provider near you?

Rx Only
The SAINT® Neuromodulation System is indicated for the treatment of Major Depressive Disorder (MDD) in adult patients who have failed to achieve satisfactory improvement from prior antidepressant medication in the current episode. The SAINT Neuromodulation System is contraindicated for: patients with non-removable conductive, ferromagnetic, or other magnetic-sensitive metal anywhere in the head or within 30cm of the stimulation coil; patients who have an active or inactive implanted device; or patients with increased intracranial pressure or intracardiac lines, intravenous pumps, or dose calculators. Consult product labeling for a complete list of contraindications, warnings, and precautions. Side effects including headache, fatigue, anxiety, and treatment-site discomfort were shown in clinical trials. Risks associated with transcranial magnetic stimulation, including seizure and worsening depression or suicidality, may exist. Results may vary.